Protection of fetuses from in utero inflammation: can MRI be the solution?
نویسندگان
چکیده
Objectives: Prenatal inflammation is a major factor associated with altered brain development in the newborn leading to neurodevelopmental diseases and enhanced susceptibility to brain damage occurring at a later stage. There is currently no treatment to alleviate the impact of prenatal inflammation on the development of the newborn. This is mainly due to the lack of non-invasive tools to detect the prenatal inflammation and its role on the maternofetal interface. We used MRI as a detection technique to evaluate the impact of inflammation on the placenta and to determine an optimal therapeutic window for the administration of anti-inflammatory treatment.
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